A story of scientific discovery and personal triumph

This compelling three-chapter docuseries chronicles the revolutionary impact of CAR T-cell therapy, pioneered by Dr. Carl June at the University of Pennsylvania, with research funding from the Leukemia & Lymphoma Society (LLS).

  • Chapter One: The History and Clinical Impact of the CAR T-Cell Therapy Revolution
  • Chapter Two: The Anatomy of Process: CAR T-Cell Therapy Treatment and Patient Pioneers
  • Chapter Three: Recovery Post-CAR T-Cell Therapy and a Revitalized Future

It follows two early trial participants: the first at Penn State and the first at Stanford University. Tim, treated for diffuse large B-cell lymphoma, returned to his challenging athletic pursuits within months of the treatment. Nearly 6 years later, he spoke of future planning with his young family. Maurice, treated for multiple myeloma, became an avid cyclist and resumed his personal expeditions with his wife—dancing along the way to celebrate the life-changing impact of the therapy.

Created by
LLS

In partnership with PIXACORE

CAR T Resource Center

CAR T Resource Hub on LLS.org (The Leukemia & Lymphoma Society)

This comprehensive resource from The Leukemia & Lymphoma Society offers detailed insights into how CAR T therapy works, its benefits, risks, and the latest advancements

LLS Educational Videos

View free education videos about survivorship, treatment, disease updates, and other topics on LLS.org.

What Is CAR T Therapy?

Learn the basics of CAR T therapy: how it works, the conditions it treats, and why it’s considered a breakthrough in cancer care.

Understanding CAR T therapy | Let’s Chat CAR T

Am I or My Loved One a Candidate for CAR T?

Discover the eligibility criteria for CAR T therapy, including the conditions it targets and the health factors that specialists evaluate.

Who is CAR T therapy for? - Let’s Chat CAR T

Understanding the CAR T Process

See a step-by-step overview of the CAR T therapy journey, from cell collection and modification to infusion and post-treatment monitoring.

CAR T Therapy Process | Step By Step Guide

When discussing CAR T therapy with your community hematologist or oncologist, consider asking:

  • Eligibility Assessment: Based on my medical history and condition, do you think CAR T therapy might be an option for me?
  • Referral Process: Can you refer me to a treatment center or specialist that offers CAR T therapy?
  • Pre-Consultation Requirements: What diagnostic tests or medical records would I need before consulting with a CAR T specialist?
  • Coordination of Care: How will you coordinate with the treatment center if I pursue CAR T therapy?
  • Alternative Treatments: What are the local treatment options available, and how do they compare to CAR T therapy?
  • Understanding Risks and Benefits: Can you help me understand the potential risks, benefits, and follow-up requirements for CAR T?
  • Post-Treatment Care: Will you oversee my care and recovery once I return from the treatment center?

When consulting with a specialist at a CAR T treatment center, consider asking:

  • Eligibility Criteria: Am I eligible for CAR T therapy based on my medical history and condition?
  • Pre-Treatment Evaluations: What testing or pre-treatment evaluations will I need?
  • Treatment Process: Can you explain the step-by-step process of CAR T therapy, including preparation, infusion, and recovery?
  • Potential Risks and Side Effects: What are the potential risks and side effects, and how are they managed at this center?
  • Expected Outcomes: What outcomes have you seen in patients with my specific diagnosis?
  • Duration of Stay: How long will I need to stay near the treatment center for monitoring and follow-up care?
  • Clinical Trials: Does this center participate in any clinical trials for CAR T therapy?
  • Coordination with Local Care Team: How will you collaborate with my local care team to ensure continuity of care?

What to Expect During and After CAR T Therapy

Explore the side effects, recovery timeline, and follow-up care needed after undergoing CAR T therapy.

What can I expect with CAR T therapy? | Let’s Chat CAR T

CAR T Therapy Center Directory

Explore the directory to find medical centers offering CAR T therapy, searchable by disease, location, patient type, and more.

CAR T Program Search

CAR T Therapy Glossary

Access a comprehensive glossary of terms related to CAR T therapy, including definitions of key concepts and medical terminology.

Glossary of Terms

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